335 First Ave Local commercial | 153 m² | À louer | New York, NY 10003

Positioned in Gramercy Park along one of Manhattan’s busiest thoroughfares, this ground-floor location offers outstanding street exposure and consistent foot traffic in a multifamily mid-rise building built in 1920. Key Features Approximately 2000 SF of space with a basement Former medical office build-out with reception, exam rooms, and support spaces Excellent frontage and visibility on 1st Avenue Located steps from Mount Sinai Beth Israel and Bellevue Hospital—ideal for healthcare or wellness use Surrounded by dense residential buildings, boutique retail, cafes, and high pedestrian traffic High ceilings, bright and open layout with large display windows Space previously fitted with multiple exam/treatment rooms, a reception/waiting area, private office, and built-in plumbing and ventilation Zoned C1-6A, suitable for medical, retail, office, or wellness tenants Prior Setup Highlights Reception/Waiting Area oriented toward the storefront At least two exam or treatment rooms, with plumbing connections available A private office/back room or staff area Separate support space for storage or records Central HVAC and proper ventilation suitable for medical or wellness operations The layout facilitates a smooth transition for tenants seeking medical, dental, aesthetic, or therapy-related services Location Benefits Walking distance to Union Square, local parks, and dynamic East Village amenities—ensuring consistent visibility and foot traffic Public transit access includes nearby subway lines and multiple bus routes Surrounded by a vibrant residential and professional tenant base (e.g. NYU, Stuyvesant Town, hospitals) with above-average walk and transit scores This space represents a rare opportunity to occupy a fully built-out commercial suite in a highly trafficked, mixed-use mid-rise building. Previously outfitted for medical use with exam rooms, reception, private office, and infrastructure in place, it offers immediate potential for practitioners, wellness brands, or boutique services. Available Immediately for Lease. Contact today to schedule a tour, review floor plans, or learn about rent and terms.